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Want to keep track of the largest startup funding deals in 2026 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The ÍÃ×ÓÏÈÉú´«Ã½ Megadeals Board.

This is a weekly feature that runs down the week’s Top 10 announced funding rounds in the U.S. Check out last week’s biggest funding deal roundup here.

This week’s list of the largest U.S. startup funding rounds was pretty much all about AI. That includes the biggest financing — a $1 billion round for , a developer of AI assistants for everyday tasks — as well as most of the rest of the Top 10. Other large fundraisers include , which is deploying AI for the home rental sector, and , an AI cybersecurity startup.

1. , $1B, AI assistants: San Francisco-based Instinct, a startup building a personal AI assistant for everyday tasks, secured $1 billion in a Series C round. , and backed the financing, which set a $10 billion valuation for the year-old company.

2. , $350M, AI for housing: EliseAI, a startup deploying AI for the home rental industry, completed a $350 million funding round at a $4 billion valuation. and led the financing for the New York-based company, which is also expanding into healthcare.

3. , $255.5M, cybersecurity: Palo Alto, California-based Armadin, an AI-native cybersecurity company focused on autonomous security, raised $255.5 million in Series B funding. and led the round, which set a valuation of more than $2.5 billion for the year-old startup.

4. , $250M, project management:  Kahua, a platform for enterprises to manage complex capital projects, picked up $250 million in growth funding from . The financing set a valuation of over $1 billion for the Alpharetta, Georgia-based company.

5. , $223M, AI infrastructure: Mountain View, California-based GMI Cloud, a provider of GPU cloud infrastructure used by AI teams to help train and run models, closed on $223 million in Series B funding as well as $445 million in debt financing. led the round, with participation from .

6. , $220M, foundational AI: General Intuition,a developer of AI models trained on videos and virtual worlds to develop skills for physical environments, secured $220 million in fresh funding. and were lead backers in the round, which set a $6.2 billion valuation for the New York-based company.

7. (tied) , $150M, physical AI: SiMa.ai, developer of a software platform for scaling physical AI applications, picked up $150 million in Series C financing at a $1.45 billion valuation. and led the round for the San Jose-based company.

7. (tied) , $150M, agentic app development: Supabase, provider of an AI-enabled open source Postgres platform for app developers, $150 million in new funding led by . The San Francisco-based startup also said it is acquiring database architecture startup .

9. , $145M, AI infrastructure: CScale, a developer of optical interconnect technology for AI data centers, emerged from stealth and says it secured $145 million in Series C funding.  , , and led the round for the Palo Alto, California-based startup.

10. , $120M, real estate: Austin-based Homeward, a startup that helps homeowners buy before selling their existing homes or get cash offers for their properties, closed on $120 million in Series D equity funding led by . The 8-year-old company also secured $330 million in debt financing.

Methodology

We tracked the largest announced rounds in the ÍÃ×ÓÏÈÉú´«Ã½ database that were raised by U.S.-based companies for the period of Sept. 26-Oct. 2, 2026. Although most announced rounds are in the database, there may be a small time lag, as some rounds are reported late in the week.

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